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JAMA Oncology Clinical Challenge
February 2017

An Aggressive Mandibular Mass

Author Affiliations
  • 1Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio
  • 2Department of Otolaryngology–Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland
JAMA Oncol. 2017;3(2):271-272. doi:10.1001/jamaoncol.2016.5648

A woman in her 70s with a history of sarcoidosis presented with progressive supraclavicular, facial, and mandibular swelling of 3 months’ duration. She reported pain with chewing, which led to a 5-kg weight loss, but denied trismus. On examination, there was craniofacial deformity with left facial preauricular swelling. The left parotid was firm and a fixed mass was felt throughout the left preauricular space, expanding into the temporomandibular joint area and zygoma. Soft-mobile lymphadenopathy was palpable in the left neck, and a firm, adherent, immobile right supraclavicular mass extended under the clavicle. Cranial nerve examination findings were normal.

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