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Comment & Response
May 18, 2017

Current Challenges Associated With Next-Generation Sequencing of Breast Cancer

Author Affiliations
  • 1Oncology Division, Wake Forest Medical School, Winston-Salem, North Carolina
JAMA Oncol. Published online May 18, 2017. doi:10.1001/jamaoncol.2017.0659

To the Editor I appreciated the nice review of the current status and promise for the use of next-generation sequencing (NGS) in identifying actionable somatic and germline molecular abnormalities as breast cancer therapeutic targets. The authors1(p262) conclude that “circulating tumor DNA analysis, once sensitive and broad enough” will enable the identification of these actionable abnormalities.

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