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Research Letter
June 22, 2017

Hospital-Based End-of-Life Care and Costs for Older Patients With Malignant Brain Tumors

Author Affiliations
  • 1Department of Radiation Oncology, University of Alabama at Birmingham
  • 2Division of Hematology-Oncology, Department of Medicine, University of Alabama at Birmingham
  • 3Department of Biostatistics and Epidemiology, University of North Texas Health Sciences Center, Fort Worth
  • 4Division of Neuro-oncology, Department of Neurology, University of Alabama at Birmingham
JAMA Oncol. Published online June 22, 2017. doi:10.1001/jamaoncol.2017.1624

Approximately half of patients with a diagnosis of primary malignant brain tumor (PMBT) or secondary malignant brain tumor (SMBT) are older than 65 years and experience disproportionate mortality and symptom burden. End-of-life care for patients with terminal cancer is often aggressive, costly, and discordant with patient preferences.1 However, a lack of knowledge remains about patterns of end-of-life care for the growing population of elderly people with a malignant brain tumor. This study compares hospital-based care and costs in the last 30 days of life for older patients with PMBT and SMBT, identifies potential risk factors for aggressive care, and evaluates the association between aggressive care and cost.

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