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Year

Day

January 12, 2017
Cancer Care Chronicles

Escalation of Commitment in Treatment Decisions Near the End of Life

Abstract Full Text
JAMA Oncol. Published online January 12, 2017. doi:10.1001/jamaoncol.2016.5490
Original Investigation

Surrogate End Points for All-Cause Mortality in Men With Localized Unfavorable-Risk Prostate Cancer Treated With Radiation Therapy vs Radiation Therapy Plus Androgen Deprivation TherapyA Secondary Analysis of a Randomized Clinical Trial

Abstract Full Text
free access
JAMA Oncol. Published online January 12, 2017. doi:10.1001/jamaoncol.2016.5983

This subgroup analysis of a randomized clinical trial of radiation therapy vs radiation therapy plus androgen deprivation therapy for prostate cancer compares the performance of 4 candidate surrogates for all-cause mortality in men with localized unfavorable-risk prostate cancer using the proportion of treatment-effect metric.

Molecular-Based Recursive Partitioning Analysis Model for Glioblastoma in the Temozolomide EraA Correlative Analysis Based on NRG Oncology RTOG 0525

Abstract Full Text
JAMA Oncol. Published online January 12, 2017. doi:10.1001/jamaoncol.2016.6020

This secondary analysis of a randomized clinical trial assesses whether molecular variables improve prognostic classification of glioblastomas treated with radiation and temozolomide.

Review

Imaging Locally Advanced, Recurrent, and Metastatic Prostate CancerA Review

Abstract Full Text
JAMA Oncol. Published online January 12, 2017. doi:10.1001/jamaoncol.2016.5840

This review examines recent developments in tumor visualization for locally advanced, recurrent, and metastatic prostate cancer.

Comment & Response

The Significance of Invasive Breast Cancer Associated With Ductal Carcinoma In Situ (DCIS) Compared With Cancer Without Associated DCIS

Abstract Full Text
JAMA Oncol. Published online January 12, 2017. doi:10.1001/jamaoncol.2016.5495
JAMA Oncology Patient Page

Cancer-Related Depression

Abstract Full Text
free access
JAMA Oncol. Published online January 12, 2017. doi:10.1001/jamaoncol.2016.5851
January 5, 2017
Viewpoint

The Diminishing Role of Whole-Brain Radiation Therapy in the Treatment of Brain Metastases

Abstract Full Text
JAMA Oncol. Published online January 5, 2017. doi:10.1001/jamaoncol.2016.5411

This Viewpoint asserts that there is limited benefit for whole-brain radiation therapy in the treatment of brain metastases.

The Changing Role of Whole-Brain RadiotherapyDemise or Time for Selective Usage?

Abstract Full Text
JAMA Oncol. Published online January 5, 2017. doi:10.1001/jamaoncol.2016.5414

This Viewpoint asserts that whole-brain radiation therapy is beneficial for the treatment of brain metastases.

Original Investigation

Association of Delayed Adjuvant Chemotherapy With Survival After Lung Cancer Surgery

Abstract Full Text
JAMA Oncol. Published online January 5, 2017. doi:10.1001/jamaoncol.2016.5829

This study assesses differences in survival according to the time interval between non–small-cell lung cancer resection and the initiation of postoperative chemotherapy to determine the association between adjuvant treatment timing and efficacy.

Brief Report

Comparison of Survival Outcomes Among Human Papillomavirus–Negative cT1-2 N1-2b Patients With Oropharyngeal Squamous Cell Cancer Treated With Upfront Surgery vs Definitive Chemoradiation TherapyAn Observational Study

Abstract Full Text
JAMA Oncol. Published online January 5, 2017. doi:10.1001/jamaoncol.2016.5769

This study compared survival outcomes among patients with newly diagnosed cT1-2 N1-2b human papillomavirus-negative oropharyngeal squamous cell carcinoma when treated with primary surgical resection vs chemoradiation.

Special Communication

Diagnosis and Management of Waldenström MacroglobulinemiaMayo Stratification of Macroglobulinemia and Risk-Adapted Therapy (mSMART) Guidelines 2016

Abstract Full Text
JAMA Oncol. Published online January 5, 2017. doi:10.1001/jamaoncol.2016.5763

This Special Communication provides consensus recommendations for a risk-adapted approach to treatment of Waldenström macroglobulinemia.

Editor's Note

Bringing Adjuvant Chemotherapy for Resected Non–Small-Cell Lung Cancer Into Real-world Practice—Better Late Than Never?

Abstract Full Text
free access
JAMA Oncol. Published online January 5, 2017. doi:10.1001/jamaoncol.2016.5798
Correction

Supplement 2 Added

Abstract Full Text
free access
JAMA Oncol. Published online January 5, 2017. doi:10.1001/jamaoncol.2016.6886
Poetry and Oncology

A Silver Lining

Abstract Full Text
JAMA Oncol. Published online January 5, 2017. doi:10.1001/jamaoncol.2016.5993
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