This phase 2 trial assesses the effect of neoadjuvant chemotherapy followed by surgery on survival in patients with metastatic gastric and gastroesophageal junction cancer.
This population-based study evaluates SEER data on the incidence and prevalence of neuroendocrine tumors over 20 years.
This case-control study using 2 cohorts attempts to identify the genetic variants associated with cisplatin-induced ototoxic effects in adult patients with testicular cancer.
This Viewpoint cites instances of how the availability of lifesaving cancer drugs in sub-Saharan Africa are increasing overall survival to argue for the increased dissemination of cost-effective or free cancer drugs.
This open-label phase 1 dose-escalation study examines whether systemic administration of HER2-specific chimeric antigen receptor–modified virus-specific T cells is safe and whether these cells have antiglioblastoma activity.
This cohort study assessed the survival impact of second primary malignant neoplasms (SMPs) in adolescents and young adults compared with that of children and older adults with the same SPMs.
This study analyzes mammography screening data from the National Mammography Database to determine the age cutoff point for screening.
This study analyzes how patient preferences and burden of disease can be incorporated into randomized clinical trials in oncology using Bayesian decision analysis and the impact that these factors have on statistical thresholds for drug approval.
This case-control study evaluates pathogenic variants in panel genes tested in women with breast cancer.
This longitudinal registry study assesses the clinical spectra and age-related penetrance in individuals with pheochromocytomas and paragangliomas and mutations in the SDHA, TMEM127, MAX, and SDHAF2 genes.
This randomized clinical trial compares the effects of metronomic chemotherapy on progression-free survival vs placebo in pediatric patients with primary extracranial, nonhematopoietic solid malignant tumors that progress after at least 2 lines of chemotherapy.
This study examines trends in patient utilization of physician-aided dying under the Death With Dignity Act in Oregon between 1998 and 2015.