The herpes simplex virus (HSV) and the varicella-zoster virus are important causes of ocular disease. It is well established that topical and oral antiviral medications speed the healing of acute dendritic or geographic epithelial lesions due to HSV,1 and that oral antiviral drugs alter the course of acute varicella-zoster virus eye disease.2 After the resolution of acute disease, some clinical scenarios warrant ongoing antiviral therapy. Establishing clear indications for ongoing treatment is a complex task. The purpose of this editorial is to summarize previous research and newer research in order to provide some basis for rational decision making in the treatment of patients with these often-complex conditions.
Baratz KH. The Role of Antiviral Therapy After the Resolution of Acute Herpes Simplex Keratitis or Acute Herpes Zoster Ophthalmicus. Arch Ophthalmol. 2012;130(1):108-110. doi:10.1001/archophthalmol.2011.379