The comments of Dr Fourman encouraging ophthalmologists to use topical aminocaproic acid for the treatment of hyphema are appreciated. In our recently published clinical study,1 patients treated with topical and systemic aminocaproic acid were compared with control subjects. The incidence of 3% secondary hemorrhage was found in the groups treated with topical and systemic aminocaproic acid compared with an incidence of 22% secondary hemorrhage found in controls. In an accompanying editorial, Goldberg2 concluded that these results deserve serious consideration regarding the treatment of traumatic hyphema.
Crouch ER, Williams PB. Topical Aminocaproic Acid in the Treatment of Patients With Traumatic Hyphema—Reply. Arch Ophthalmol. 1998;116(3):395-396. doi: