The article by Herndon et al1 published in the September 1997 issue of the ARCHIVES confirms earlier observations on the relation between corneal thickness and applanation pressure. In view of the reduced number of endothelial cells2,3 and the direct involvement of the corneal endothelial cell in pseudoexfoliations syndrome (PXS),4,5 we suggest that PXS6 should also be considered in studies concerning corneal thickness as a sign of subtle corneal endothelial decompensation. In the Herndon et al study we would be interested to know how many of the patients with ocular hypertension also showed evidence of this syndrome.
Naumann GOH. Corneal Thickness and Applanation Pressure. Arch Ophthalmol. 1998;116(5):701. doi: