Mintz-Hittner and Fernandez1 contribute
to the debate concerning the influence of age on treatment outcome in amblyopia.
They report significant improvements in the visual acuity of 36 children between
the ages of 7.0 and 10.3 years undergoing occlusion or penalization therapy.
These are heartening results but are not unexpected; we now know that even
adults with amblyopia demonstrate residual plasticity of the visual system.2 Levi's remark3
that failure to achieve improvement in the older amblyopic child may "reflect
the very real difficulties in maintaining patient (or clinician) motivation
or the failure to use the most efficacious treatment modalities" now appears
Moseley M, Fielder A, Stewart C. Compliance With Amblyopia Therapy. Arch Ophthalmol. 2001;119(8):1226. doi: