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Comment & Response
March 2014

Statin Use and Cataract—Reply

Author Affiliations
  • 1VA North Texas Health Care System, Dallas
  • 2Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas
  • 3Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas
  • 4Wilford Hall Ambulatory Surgery Center, San Antonio, Texas
  • 5San Antonio Military Medical Center, San Antonio, Texas
JAMA Ophthalmol. 2014;132(3):364-365. doi:10.1001/jamaophthalmol.2014.40

In Reply Dr Kostis and Ms Dobrzynski suggest that cataract surgery would be a better hard end point than clinical diagnoses of cataract. We agree; however, this outcome requires a longer follow-up period than was available in our study (approximately 4.5 years). They also propose that statin effects may vary with patients’ age and stage of cataract development. We appreciate these ideas and agree that such a study should be pursued. Owing to the relatively small sample size of our propensity score–matched cohort, further subgroup analysis was not feasible.

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