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Observation
June 2014

Successful Long-term Management of Iris Flocculi and Miosis in a Patient With a Strong Family History of Thoracic Aortic Aneurysms and Dissections Associated With an MYH11 Mutation

Author Affiliations
  • 1Department of Ophthalmology and Visual Sciences, University of Iowa Carver College of Medicine, Iowa City
JAMA Ophthalmol. 2014;132(6):778-780. doi:10.1001/jamaophthalmol.2014.294

Primary pigmented epithelial iris cysts of the pupillary margin, or iris flocculi, are usually asymptomatic but can obstruct the pupil and decrease vision.1 We report successful long-term surgical management of a patient with visually significant iris flocculi and miosis. These were related to a strong family history of thoracic aortic aneurysms and aortic dissections (TAAD) associated with a mutation in the myosin, heavy chain 11, smooth muscle gene (MYH11).

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