Copyright 2014 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
True neoplasms can arise from pigment epithelium of the iris, ciliary body, and retina (retinal pigment epithelium [RPE]).1- 4 We report a large adenocarcinoma of RPE that was a diagnostic challenge based on clinical features, cytopathology, and immunohistochemistry. However, with routine histopathology of the enucleated eye, the diagnosis of RPE adenocarcinoma was established.
Shields JA, Eagle RC, Dutton J, Ehya H, Shields CL. Adenocarcinoma of the Retinal Pigment EpitheliumClinicopathologic Correlation With Paradoxical Immunohistochemical Findings. JAMA Ophthalmol. 2014;132(10):1249-1252. doi:10.1001/jamaophthalmol.2014.2369