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Optic disc pit (ODP) is a rare congenital cavitation in the optic nerve head frequently associated with serous detachments of the macula, ODP maculopathy (ODP-M), and subsequent visual decline.1 Optic disc pit maculopathy is preceded by development of a schisis cavity due to accumulation of intraretinal fluid from the ODP. The source of the fluid remains controversial and 4 mechanisms have been hypothesized: (1) fluid from the vitreous cavity2; (2) cerebrospinal fluid originating from the subarachnoid space3; (3) fluid originating from the orbital space surrounding the dura1; and (4) fluid from leaky blood vessels at the pit base.1
Coca MN, Tofigh S, Elkeeb A, Godley BF. Optic Disc Pit Maculopathy Recurring in the Absence of Vitreous Gel. JAMA Ophthalmol. 2014;132(11):1375-1376. doi:10.1001/jamaophthalmol.2014.2054