Anti–vascular endothelial growth factor (VEGF) agents are used for the treatment of neovascular age-related macular degeneration (AMD). These agents may also affect wound healing and decrease bleb vascularity after trabeculectomy.1 We are not aware of any reports of the effects of anti-VEGF agents on wound healing after glaucoma drainage implant (GDI) surgery. We describe reduced bleb vascularity and unexpectedly prolonged hypotony in 2 patients after GDI surgery who received multiple injections of anti-VEGF agents.
Hoguet A, Parrish RK. Unexpected Hypotony After Glaucoma Drainage Implant Surgery Associated With Anti–Vascular Endothelial Growth Factor Treatment. JAMA Ophthalmol. 2015;133(3):349-350. doi:10.1001/jamaophthalmol.2014.5058