[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.158.167.137. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Views 473
Citations 0
Observation
March 2015

Unexpected Hypotony After Glaucoma Drainage Implant Surgery Associated With Anti–Vascular Endothelial Growth Factor Treatment

Author Affiliations
  • 1Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston
  • 2Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida
JAMA Ophthalmol. 2015;133(3):349-350. doi:10.1001/jamaophthalmol.2014.5058

Anti–vascular endothelial growth factor (VEGF) agents are used for the treatment of neovascular age-related macular degeneration (AMD). These agents may also affect wound healing and decrease bleb vascularity after trabeculectomy.1 We are not aware of any reports of the effects of anti-VEGF agents on wound healing after glaucoma drainage implant (GDI) surgery. We describe reduced bleb vascularity and unexpectedly prolonged hypotony in 2 patients after GDI surgery who received multiple injections of anti-VEGF agents.

First Page Preview View Large
First page PDF preview
First page PDF preview
×