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To the Editor We commend Mititelu et al1 on their recent study of hydroxychloroquine toxic effects but take issue with their conclusion. We believe prevention rather than early detection is best practice. Hydroxychloroquine is dosed by lean (“ideal”) body weight, which is based purely on height and sex. It is a hypothetical concept that excludes body fat in determining a person’s weight. Hence, shorter patients will have a lower lean body weight.
Walvick MD, Ngo CH. Prevention of Hydroxychloroquine-Related Retinal Toxic Effects. JAMA Ophthalmol. 2015;133(4):492. doi:10.1001/jamaophthalmol.2014.3254