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July 2015

Chikungunya Virus Infection and Bilateral Stromal Keratouveitis

Author Affiliations
  • 1Department of Ophthalmology, Hôpital Bicêtre, Assistance Publique–Hôpitaux de Paris, Paris-Sud University, Le Kremlin–Bicêtre, France
  • 2Laboratoire de Virologie Moléculaire et Structurale, Centre National de la Recherche Scientifique, Gif-sur-Yvette, France
  • 3Department of Virology, Hôpital Paul-Brousse, Assistance Publique–Hôpitaux de Paris, Paris-Sud University, Villejuif, France
  • 4French Armed Forces Biomedical Research Institute (IRBA), Marseille, France

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JAMA Ophthalmol. 2015;133(7):849-850. doi:10.1001/jamaophthalmol.2015.0698

Chikungunya virus (CHIKV) is a mosquito-borne viral disease caused by an arbovirus from the Togaviridae family. It is endemic in parts of Africa and Southeast Asia and on the Indian subcontinent.1 In December 2013, autochthonous chikungunya cases were confirmed on Saint-Martin island in the French West Indies. This was the first time that local transmission of CHIKV had been reported in the Americas.2 Since then, CHIKV spread to most Caribbean islands with hundreds of thousands of cases. The typical clinical signs of the disease are acute fever, severe arthralgia, and skin rash. Complications include myocarditis, hepatitis, and neurological and ocular disorders, including a variety of anterior and posterior segment manifestations.1,3,4

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