A man in his 40s reported bilateral blurry vision and photophobia for the 2 days since he sprayed polyurethane foam insulation. He denied direct ocular exposure and had used a respirator with a face shield. An examination revealed numerous discrete intraepithelial corneal opacities without inflammatory signs, punctate staining, or elevated intraocular pressure (Figure). Symptoms and examination findings improved slightly during the next 24 hours and had resolved completely 2 weeks later without treatment.
Michelotti MM, Gupta C, Hood CT. Persistent Amine Keratopathy Secondary to Indirect Exposure to Spray Polyurethane Foam Insulation. JAMA Ophthalmol. 2015;133(6):e1584. doi:10.1001/jamaophthalmol.2015.84