Invasion of the retina by malignant choroidal melanoma is relatively common, occurring in 23% to 40% of enucleated eyes.1,2 Limited invasion typically occurs after the tumor penetrates Bruch’s membrane and migrates into overlying retina. Widespread proliferation of melanoma cells within the vitreous and invasion of nonadjacent retina are rare.1- 3 We report a case of malignant melanoma with preretinal membrane proliferation of tumor and perivascular retinal invasion, clinically resembling retinitis pigmentosa.
Bhavsar AR, Sandler DR, Maltry AC. Diffuse Pigmentary Retinopathy and Preretinal and Perivascular Intraretinal Invasion of Choroidal Malignant Melanoma. JAMA Ophthalmol. 2015;133(9):1092-1094. doi:10.1001/jamaophthalmol.2015.1817