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To the Editor In their article titled “Variability of Tear Osmolarity in Patients With Dry Eye,” Bunya et al1 describe significant variability in TearLab osmolarity readings of clinical populations (control participants, patients with blepharitis, and patients with Sjögren syndrome) and suggest that this confounds clinical interpretation of tear osmolarity measures.
Downie LE, Vingrys AJ. Accuracy of Laboratory Assays in Ophthalmic Practice. JAMA Ophthalmol. 2015;133(12):1480. doi:10.1001/jamaophthalmol.2015.3856