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Ophthalmic Images
November 12, 2015

Myopic Cleavage of Retinal Nerve Fiber Layer Assessed by Split-Spectrum Amplitude-Decorrelation Angiography Optical Coherence Tomography

Author Affiliations
  • 1Division of Glaucoma, Sensho-kai Eye Institute, Uji, Kyoto, Japan
JAMA Ophthalmol. 2015;133(11):e152143. doi:10.1001/jamaophthalmol.2015.2143

Myopic cleavage of the retinal nerve fiber layer, characterized by cuneiformic dark areas near the major retinal vessels, was first reported in 19921 and later confirmed.24 The cleavage occurs at the superficial retina in eyes with high myopia or epiretinal membrane and may be associated with visual field defects.4 Stress, such as myopic cleavage of the retinal nerve fiber layer, deformation of the lamina cribrosa, and stretching and compression of the retinal nerve fiber layer at the disc margin and scleral ridge,5 may lead to nerve fiber loss in eyes with high myopia.

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