In Reply We thank De Jong and colleagues for their interest in our article and for their continued contributions to the field. We too recognize that new observations must always be viewed with caution. While the numbers may seem small (140 eyes), they represent the largest published series, to our knowledge, with follow-up ranging from 6 to 104 months. Our results closely parallel those previously reported by Suzuki et al1 (with longer follow-up) using a slightly different technique.
Yannuzzi NA, Francis JH, Abramson DH. Incidence of Orbital Recurrence After Enucleation or Ophthalmic Artery Chemosurgery for Advanced Intraocular Retinoblastoma—Reply. JAMA Ophthalmol. 2016;134(1):114-115. doi:10.1001/jamaophthalmol.2015.4581