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Invited Commentary
April 2016

Optical Coherence Tomographic Angiography in Diabetic Macular Ischemia A New Step Forward

Author Affiliations
  • 1Centre de l’Odéon, Paris, France
  • 2Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, Créteil, France
  • 3Department of Biomedical and Surgical Sciences, Section of Ophthalmology, University of Perugia, S. Maria della Misericordia Hospital, Perugia, Italy
JAMA Ophthalmol. 2016;134(4):373-374. doi:10.1001/jamaophthalmol.2015.4821

The fovea is a highly specialized macular region with a unique microanatomy that represents the area of greatest visual acuity. The fovea mainly consists of different structures that are highly dependent on multilayered capillary plexa for metabolic exchanges. Perifoveal capillary arcade disruption, enlargement of the foveal avascular zone, and reduction of foveal capillary density evaluated with fluorescein angiography (FA) have been negatively correlated with visual acuity, suggesting that they might be useful in evaluating foveal health status.1

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