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Observation
May 2016

Spontaneous Closure of a Full-Thickness Macular Hole With Conversion to Exudative Age-Related Macular Degeneration

Author Affiliations
  • 1Department of Ophthalmology, Stein Eye Institute, University of California, Los Angeles
JAMA Ophthalmol. 2016;134(5):604-606. doi:10.1001/jamaophthalmol.2016.0020

Macular hole formation is thought to occur secondary to anteroposterior forces and traction at the vitreofoveal interface. Although it is uncommon, there have been numerous reports of spontaneous closures of macular holes.1,2 These closures are triggered by the release of anterior traction at the vitreofoveal interface or glial proliferation from retinal or epiretinal tissue. We report a case of spontaneous closure of a full-thickness macular hole (FTMH) after conversion from nonexudative to exudative age-related macular degeneration (AMD).

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