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Observation
August 2016

Phase-Variance Optical Coherence Tomographic Angiography Imaging of Choroidal Perfusion Changes Associated With Acute Posterior Multifocal Placoid Pigment Epitheliopathy

Author Affiliations
  • 1Department of Ophthalmology and Vision Science, University of California, Davis Eye Center, Sacramento
  • 2Beckman Laser Institute Korea and Biomedical Engineering, Dankook University, Cheonan, Chungnam, South Korea
JAMA Ophthalmol. 2016;134(8):943-945. doi:10.1001/jamaophthalmol.2016.1645

Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is characterized by bilateral multiple placoid white-gray lesions of the posterior pole at the level of the retinal pigment epithelium (RPE) and/or choriocapillaris, which self-resolve with recovery of vision.1,2 The etiology is unknown, but APMPPE has been associated with viral prodromes and vasculitis. The placoid lesions are thought to represent focal RPE inflammation or choriocapillaris ischemia based on fluorescein angiogram findings of early hypofluorescence and late hyperfluorescence.

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