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An African American woman in her mid-20s was referred for evaluation of bilateral iris anomaly. Her only symptom was mild glare from lights at night, which she described as stable and tolerable for many years. Visual acuity prior to dilation was 20/40 OD and 20/30 + 1 OS without improvement using pinhole. Intraocular pressure was 10 mm Hg OD and 12 mm Hg OS. Examination was remarkable only for bilateral persistent pupillary membranes (Figure). Pharmacological dilation provided a view of both fundi. Given her visual acuity, minimal symptoms, and lack of desire for surgical or laser intervention, she was observed.
Doyle JJ, Reddy AK. Bilateral Persistent Pupillary Membranes. JAMA Ophthalmol. 2016;134(7):e160030. doi:10.1001/jamaophthalmol.2016.0030