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Brief Report
November 2016

Photoreceptor Arrangement Changes Secondary to Choroidal Nevus

Author Affiliations
  • 1Department of Ophthalmology, Ribeirão Preto School of Medicine, University of São Paulo, Ribeirão Preto, Brazil
  • 2Department of Ophthalmology, University of Cincinnati College of Medicine, Cincinnati, Ohio
  • 3Department of Ophthalmology, Wills Eye, Philadelphia, Pennsylvania
JAMA Ophthalmol. 2016;134(11):1315-1319. doi:10.1001/jamaophthalmol.2016.3633

Importance  Although mostly asymptomatic, patients with choroidal nevi carry a moderate risk for malignant transformation and visual loss. A novel noninvasive imaging assessment could change the current clinical evaluation of choroidal nevi.

Observation  Three patients with a recent diagnosis of choroidal nevi underwent a novel adaptive optical assessment that detected potential photoreceptor abnormalities in the retina overlying the choroidal nevi.

Conclusions and Relevance  Adaptive optics imaging may provide high-resolution en face images of retinal structural changes in the photoreceptor mosaic overlying the choroidal nevi. Cone attenuation may be an important component of structural damage in choroidal nevi and may correlate and possibly predict functional visual loss.