An Asian woman in her 60s with glaucoma but no macular degeneration was referred to the retina clinic for bilateral “foveal sparkles.” Her ocular, medical, family, and medication histories revealed nothing contributory. She had no visual complaints, and her visual acuity was 20/20 OD and OS with no afferent pupillary defect. Extraocular movements and visual fields by confrontation were full in both eyes. Slitlamp examination of the anterior segment was unremarkable in both eyes. Dilated fundus examination showed bilateral intraretinal round, yellow, glistening deposits in the fovea, and optical coherence tomography (OCT) indicated that these crystals were in the inner layers of the foveal region (Figure 1).
Choi RY, Chortkoff SC, Gorusupudi A, Bernstein PS. Crystalline Maculopathy Associated With High-Dose Lutein Supplementation. JAMA Ophthalmol. 2016;134(12):1445-1448. doi:10.1001/jamaophthalmol.2016.4117