A black woman in her early 40s with an unremarkable medical history presented with a pigmented conjunctival lesion of the right eye that had been present since childhood but had been increasing in size for the past few months (Figure, A). Tumor excision was performed under general anesthesia (using a “no-touch technique” as described previously1,2). Histological analysis showed conjunctival melanoma (Figure, B). The clinical stage of the tumor was T1aN0M0 according to the seventh edition of the American Joint Committee on Cancer staging system for conjunctival melanoma.2 No mutations were found on the BRAF gene (exon 15), NRAS gene (codons 12, 13, 61, 117, and 146), or C-KIT gene (exons 11, 13, and 17). Adjuvant brachytherapy with iodine plaque was performed because of the invasion of the substantia propria.
Lemaitre S, Fréneaux P, Cassoux N. Conjunctival Melanoma in a Black Patient. JAMA Ophthalmol. 2016;134(11):e162726. doi:10.1001/jamaophthalmol.2016.2726