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Ophthalmic Images
December 8, 2016

Angiolymphoid Hyperplasia With Eosinophilia of the Conjunctiva

Author Affiliations
  • 1Department of Pathology, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana
  • 2Department of Ophthalmology, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana
JAMA Ophthalmol. 2016;134(12):e162849. doi:10.1001/jamaophthalmol.2016.2849

A teenage girl with an unremarkable medical history presented with a localized papillomatous swelling of the conjunctiva in the lower quadrant of the right eye (Figure, A). She had first noticed it 4 months before consulting. The lesion was initially asymptomatic but started itching 3 months later. Complete ophthalmologic examination, including fundus examination and fluorescein testing of the ocular surface, found no other significant abnormality. Blood test results showed no eosinophilia. Histopathological examination of a first resection revealed typical signs of angiolymphoid hyperplasia with eosinophilia (Figure, B). Often mistaken for Kimura disease, it is a benign and chronic inflammatory disorder that commonly presents as subcutaneous masses in the head and neck region of middle-aged men. Periocular (eyelids, tear duct) manifestations of the disease have been reported.1,2 After complete resection, the patient showed no sign of recurrence at 1 year.

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