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JAMA Ophthalmology Clinical Challenge
February 2017

The Masquerade Syndrome

Author Affiliations
  • 1Department of Ophthalmology, University of California, San Francisco
JAMA Ophthalmol. 2017;135(2):161-162. doi:10.1001/jamaophthalmol.2016.2890

A man in his 50s with a history of basal cell carcinoma that was resected from the right medial canthus was referred from an outside ophthalmologist with right-sided ptosis, conjunctival hyperemia, and recurrent central corneal erosions. He complained of right ocular irritation, redness, and discharge that had begun shortly after removal of the eyelid lesion 2 years prior. He was prescribed a treatment regimen for blepharitis, which subsequently included topical tobramycin-dexamethasone ointment, with little improvement in symptoms. Eight months prior to referral, he developed a progressive right blepharoptosis followed by recurrent corneal erosions, which was treated with bandage contact lenses.

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