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JAMA Ophthalmology Clinical Challenge
December 29, 2016

Acute Eye Pain Following Prolonged Face-Down Positioning in a Patient With Marfan Syndrome

Author Affiliations
  • 1Department of Ophthalmology, Baylor College of Medicine–Cullen Eye Institute, Houston, Texas
JAMA Ophthalmol. Published online December 29, 2016. doi:10.1001/jamaophthalmol.2016.3778

A woman in her late teens with Marfan syndrome and a history of dislocated lenses presented with blurry vision, pain, and photophobia in her right eye. Her symptoms began 6 hours before presentation after she had been napping face-down on her desk for 30 minutes. Her medical history included aortic repair and cervical spine abnormalities. Her ocular history was pertinent for high myopia and contact lens wear, a posteriorly dislocated crystalline lens suspended in the vitreous cavity in her right eye, and a superotemporally subluxated crystalline lens in her left eye. Her lenses had been observed for years without intervention. The patient’s family history was unknown because she was adopted. Her medications included oral aspirin and irbesartan.

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