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Invited Commentary
January 12, 2017

The Association of Systemic Medication and Disease With Intraocular Pressure

Author Affiliations
  • 1National Institute of Health Research Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust, and University College London Institute of Ophthalmology, London, England
  • 2Integrative Epidemiology Research Group, University College London Institute of Ophthalmology, London, England
  • 3Department of Epidemiology, Glaucoma Research Unit, Moorfields Eye Hospital, London, England
  • 4Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, England
JAMA Ophthalmol. Published online January 12, 2017. doi:10.1001/jamaophthalmol.2016.5335

Ho and colleagues1 studied the cross-sectional associations between common systemic medication use and intraocular pressure (IOP) in the Singapore Epidemiology of Eye Diseases (SEED) study of a population-based cohort. Examining associations with systemic medications is of interest for 2 main reasons. First, understanding such associations may guide our management of patients with glaucoma who are receiving treatment for systemic comorbidities. Second, unexpected associations may point to previously unknown biological mechanisms underlying the regulation of IOP, which may in turn lead to new treatments.

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