In previous studies,1- 3 white persons had notably smaller optic discs than Hispanics who had smaller optic nerve heads than Asians. The optic discs were largest in African Americans. Considering this race dependence of the optic disc size, we conducted this study to evaluate, whether within a circumscribed group of white subjects, the size of the optic disc depends on the pigmentation of the individual. As measure for pigmentation, we took the color of the iris.
Budde WM, Velten IM, Jonas JB. Optic Disc Size and Iris Color. Arch Ophthalmol. 1998;116(4):545. doi: