Laboratory Science
June 1998

The Effect of Age on the Retardation of Axial Elongation Following a Lensectomy in Infant Monkeys

Author Affiliations

From the Yerkes Regional Primate Research Center and Emory Eye Center, Emory University School of Medicine, Atlanta, Ga.


Copyright 1998 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.1998

Arch Ophthalmol. 1998;116(6):781-784. doi:10.1001/archopht.116.6.781

Objective  To determine the effect of age on the retardation of axial elongation in neonatal monkey eyes following the extraction of the crystalline lens.

Methods  A monocular lensectomy was performed on 4 rhesus monkeys when they were 4 days, 2 weeks, 7.5 months, and 1 year of age. Longitudinal measurements of axial lengths and keratometry readings were made.

Results  The aphakic eye was 1.7 mm shorter than the unmanipulated fellow eye in the monkey undergoing surgery at 4 days of age and 1.1 mm shorter in the monkey undergoing surgery at 2 weeks of age. However, the aphakic eyes were only 0.2 mm and 0.1 mm shorter than their unmanipulated fellow eyes, respectively, in the monkeys undergoing surgery at 7.5 months and 1 year of age.

Conclusions  The retardation of axial elongation following a lensectomy in infantile monkey eyes is age dependent. Little effect is observed in monkeys aged 7.5 months or older.