A 34-YEAR-OLD man complained of gradual decreased vision in the right eye of 2 years' duration. He denied symptoms in his left eye. His medical history was significant for non–insulin-dependent diabetes mellitus for 8 years. He denied hypertension, hemoglobinopathies, or other systemic or vascular disease.
Visual acuity was counting fingers OD, 20/30 OS. Slitlamp examination revealed iris neovascularization in the right eye. Funduscopic examination of the right and left eyes revealed clear media, scattered dot and blot hemorrhages, cotton-wool spots, bilateral neovascularization of the disc, markedly sheathed retinal arterioles, venous beading, and featureless peripheral retina (Figure 1). A fundus map1 of the fluorescein angiography showed bilateral neovascularization of the disc with severe capillary nonperfusion in both eyes everywhere but in the peripapillary region and nasal macula (Figure 2).
Greven CM, Hackel RE, Slusher MM. Capillary Nonperfusion of the Retina in Diabetes Mellitus. Arch Ophthalmol. 1998;116(9):1260-1261. doi:10.1001/archopht.116.9.1260