Band keratopathy and calcification of the conjunctiva is reported in 18 cases of hypercalcemia and in another case in which the calcium level of the blood may be presumed to have been elevated previously. The hypercalcemia was due to hyperparathyroidism in 4 cases, to vitamin D poisoning in 5 cases and to sarcoidosis in 2 cases. In the remaining 8 cases it was associated with severe renal damage, owing, in some of the cases, to a high calcium and high alkali intake. The corneal opacity consisted of paralimbal opacification of the cornea extending 2 to 3 mm axialward in the palpebral fissure. Many of the patients had nephrocalcinosis of nephrolithiasis, and the process occurring in the kidneys was thought to be analogous to that occurring in the cornea.
A look at the past . . .. Arch Ophthalmol. 1998;116(12):1632. doi:10.1001/archopht.116.12.1632