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From the Archives of the Archives
December 1998

A look at the past . . .

Arch Ophthalmol. 1998;116(12):1680. doi:10.1001/archopht.116.12.1680

Within recent years much has been written by the pathologists about a type of tumor variously designated by the names "myoblastic myoma," "myoblastoma," "rhabdomyoma," and "granular cell myoblastoma." . . . The characteristic microscopic features may be summarized as follows: (1) large polyhedral cells, 20 to 60 microns in diameter, constitute a nodular accumulation of neoplastic cells; (2) the cytoplasm stains only faintly with eosin and contains many coarse neutrophilic granules; (3) cross or longitudinal striations are rarely seen. . . . Granular cell myoblastoma is a relatively common tumor and widely distributed throughout the body. Since its occurrence in the orbit is rare, 2 cases are reported. The tumors in these cases presented no characteristic clinical picture, and the differential diagnosis was purely a histologic one. The tumor is more commonly benign, but in 1 of the present 2 cases it was malignant.

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