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Editorial
April 2001

Once Again High Tech Meets Low Tech on Chromosome 6

Arch Ophthalmol. 2001;119(4):573-575. doi:10.1001/archopht.119.4.573

DONOSO ET AL 1 are to be congratulated on their research of the autosomal dominant Stargardt disease gene (STGD3). This study contains some extremely complex issues that require some clarification, as well as some basic and simple findings that should be emphasized. The basic issues center on genealogy, phenotype classification (lumping vs splitting), genotype and haplotype analysis, and statistics.

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