CHOROIDAL MELANOMA is the most common primary ocular malignancy, with some 1500 new cases reported yearly in the United States. These tumors are both sight- and life-threatening, with approximately a 10% to 30% five-year mortality rate owing to systemic metastasis, depending on tumor size. Despite the major morbidity and mortality from these tumors, the condition occurs infrequently enough in any single ophthalmic practice of considerable size that clinical expertise in the condition had been difficult to accumulate in years past. Even the accurate diagnosis of choroidal melanoma had been sufficiently difficult to make, and an unfortunate fraction of eyes enucleated were found to have some other condition.
Sieving PA. Fifteen Years of WorkThe COMS Outcomes for Medium-Sized Choroidal Melanoma. Arch Ophthalmol. 2001;119(7):1067-1068. doi:10.1001/archopht.119.7.1067