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Clinicopathologic Reports, Case Reports and Small Case Series
October 2001

Retinal Periphlebitis as Zoster Sine Herpete

Arch Ophthalmol. 2001;119(10):1550-1552. doi:

Although infection with varicella-zoster virus (VZV) has been known to cause occlusive retinal arteritis leading to acute retinal necrosis1 in both immunocompetent and immunocompromised patients, retinal periphlebitis is a rare manifestation of varicella-zoster ophthalmicus. We examined 2 immunocompetent patients with unilateral retinal periphlebitis and iridocyclitis without cutaneous eruptions associated with positive VZV genomes in the aqueous fluid. One patient had a fundus appearance compatible with that of frosted branch angiitis, suggesting a possible correlation between one form of frosted branch angiitis and a VZV infection.

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