WHEN SEEN by us a 55-year-old woman and her 53-year-old brother were
noted to have bilateral multiple eyelid cysts, which measured 1 to 3 mm (Figure 1), that they reported as first apparent
during their early 20s. Both had palmoplantar hyperkeratosis (Figure 2). The fingernails and toenails were brittle, furrowed,
and spooned (Figure 3). Both of
the subjects were edentulous (Figure 4),
their hair was sparse and fine, and they had scanty eyelashes and eyebrows.
The sister had decreased salivary gland secretion and vaginal dryness, whereas
the brother experienced excessive sweating and had undergone bilateral stellate
sympathectomies. They were progeny of a nonconsanguineous marriage with no
other affected family members.
Mallaiah U, Dickinson J. Bilateral Multiple Eyelid Apocrine Hidrocystomas and Ectodermal Dysplasia. Arch Ophthalmol. 2001;119(12):1866-1867. doi:10.1001/archopht.119.12.1866