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February 2002

Retinal Detachment and Culture-Proven Bacterial Endophthalmitis in the EVS

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Copyright 2002 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2002

Arch Ophthalmol. 2002;120(2):230. doi:

We read with great interest the study by Drs Doft, Kelsey, Wisniewski, and the Endophthalmitis Vitrectomy Study (EVS) Group concerning retinal detachment in the EVS.1 In their study, the rate of retinal detachment was related to the initial microbial pathogenic findings, with higher rates seen for the more virulent organisms. Their results also showed that the retinal detachment rate was significantly lower (P = .03) in eyes treated with systemic antibiotics (11/206; 5.3%) compared with those not treated with systemic antibiotics (224/214; 11.2%).1 The authors state that "this result was owing to chance" because they could not "think of any logical reason why systemic antibiotics would result in a decreased retinal detachment rate." Their result was in "apparent" conflict with the EVS, in which the overall visual results were the same for patients who received systemic antibiotics and those who did not.2

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