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Photo Essay
August 2002

Symmetric Peripheral Iris Depigmentation in Vogt-Koyanagi-Harada Syndrome

Arch Ophthalmol. 2002;120(8):1104-1105. doi:10.1001/archopht.120.8.1104

A 13-YEAR-OLD Israeli girl of Moroccan ancestry was referred for the evaluation of chronic bilateral panuveitis. Four years earlier she had developed diffuse vitiligo after sustaining a severe sunburn (Figure 1). Four months prior to her initial symptoms, she noted the onset of severe headaches and decreased visual acuity. An ophthalmic evaluation revealed anterior uveitis, elevated intraocular pressure, and ultrasonographic evidence of bilateral vitritis. Treatment consisted of topical dexamethasone sodium phosphate, timolol, and laser iridotomy for iris bombé in the right eye. There was no history of ocular trauma or surgery.

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