A 6-YEAR-OLD BOY sought treatment with a yellowish-white cystic epibulbar
nodule (Figure 1), white gingival
lesions (Figure 2), and cervical
lymphadenopathy. Histological examination of the nodule revealed eosinophilic
granuloma (Figure 3) with positive
CD1a antibody staining for Langerhans cell histiocytosis (Figure 4). Magnetic resonance imaging of the brain demonstrated
mastoid bone infiltration. Chemotherapy and radiation therapy were performed.
Melamud A, Efrat M, Sova Y, Hod Y, Geyer O. Epibulbar Nodule as a Symptom of Langerhans Cell Histiocytosis. Arch Ophthalmol. 2002;120(10):1400-1401. doi:10.1001/archopht.120.10.1400