Copyright 2002 American Medical Association. All Rights Reserved.
Applicable FARS/DFARS Restrictions Apply to Government Use.2002
A 40-YEAR-OLD MAN was referred to our eye center because of blurry vision
in both eyes. His medical history was significant for osteogenic sarcoma originating
in the right tibia with known bone, pulmonary, and brain metastases. He had
been previously treated with chemotherapy and radiation therapy. He was admitted
to the hospital with a hemoglobin level of 2.5 g/dL and transfused with 5
U of packed red blood cells. He experienced sudden onset of blurry vision
1 day after the transfusion. Best-corrected visual acuities were 20/60 OD
and 20/70 OS. The results of his ophthalmic examination were normal, except
for the dilated fundus examination. Multiple Roth spots, located primarily
within the posterior pole, were observed in both eyes (Figure 1). Hemorrhages were present in the macular region and were
associated with retinal thickening that was most likely responsible for the
decrease in vision. Fluorescein angiography did not reveal any leakage of
fluid into the macular region.
Pomeranz HD. Roth Spots. Arch Ophthalmol. 2002;120(11):1596. doi:10.1001/archopht.120.11.1596