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From the Archives of the Archives
January 1999

A look at the past . . .

Arch Ophthalmol. 1999;117(1):122. doi:10.1001/archopht.117.1.122

VAN DUYSE AND VAN SCHEVENSTEEN observed, in the person of a farmer aged fifty-four, a leucosarcoma involving the greater part of the inner half of the iris, extending to the iris angle, touching the cornea, uniformly red, pervaded with vessels, and entirely free from pigment. There were no signs of inflammation, but the tension was increased. The authors discuss the clinical differentiation of this from other forms of tumor of the iris. No pigment was found in the tumor, which proved to be a spindle-celled sarcoma arising from the adventitia of the vessels. The region of Schlemm's canal, a portion of the ciliary body, and the anterior portion of the suprachoroidal space were involved; the lens was atrophic and compressed; and the detached retina had undergone cystic degeneration. Leucosarcoma of the iris is four times as rare as melanosarcoma. Both lead to metastases less frequently than sarcoma of the choroid, because recognized and removed earlier than the latter.