[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Citations 0
May 1999

Roles of Cytokines in Diabetic Retinopathy

Arch Ophthalmol. 1999;117(5):700-701. doi:

Preretinal proliferative membrane formation, which is regulated by various cytokines, is a very important step in the pathogenesis of proliferative diabetic retinopathy.1 In addition to vascular endothelial growth factor, transforming growth factor β2 (TGF-β2) has been shown to play a key role in preretinal membrane formation caused by retinal metabolic abnormalities. Interleukin 6 (IL-6) has also been reported to be involved in the pathogenesis of diabetic retinopathy.2 In this study, to investigate the roles of these cytokines in the pathogenesis of diabetic retinopathy, we searched for systemic and/or ocular factors relevant to TGF-β2 and IL-6 in diabetic eyes.

First Page Preview View Large
First page PDF preview
First page PDF preview