Keratoprosthesis is the only solution to corneal blindness that cannot be treated by penetrating keratoplasty. Legeais et al1 and Legeais and Renard2 have reported clinical results with second-generation colonizable keratoprosthesis (Kpro) in the past 3 years. Some of the clinical failures were due to endophthalmitis, retroprosthetic membrane, or cataract formation. The second-generation optic (artificial cornea) of keratoprosthesis (Biokpro II; FCI, Paris, France) has a refractive power (42.2 diopters), thickness (550 µm), and diameter (7 mm) much like those of the human cornea.2 It should therefore make intraocular surgery possible.2 The use of biocompatible material (polytetrafluoroethylene) that can be colonized by host keratocytes also helps to integrate the alloplastic material of the haptic into the recipient cornea.3,4 The optic-haptic junction is formed by the chemical fusion of the optic (soft polydimethylsiloxane copolymer coated with polyvinylpyrrolidone) with its supporting colonizable skirt (polytetrafluoroethylene). These features should provide a better mechanical stability and avoid extrusion of the prosthesis even after the mechanical stress associated with intraocular surgery.
Legeais JM, Ellies PD, Dighiero P, Renard G. Phacoemulsification in a Patient With an Artificial Cornea. Arch Ophthalmol. 1999;117(12):1669. doi: