MANAGEMENT OF corneal infiltrates in contact lens wearers is a surprisingly complex and controversial topic. The term infiltrates includes a spectrum of corneal findings. Although contact lens–associated corneal infiltrates are usually considered sterile in contrast to infected ulcers, they can be sterile or infected. It is important to distinguish infected from sterile infiltrates because the management of the former requires intensive topical antibiotics and the latter may benefit from topical corticosteroids, which should generally be avoided in infected ulcers. In current clinical practice cultures of small corneal infiltrates are rarely performed, so the diagnosis is primarily clinical.
Cohen EJ. Management of Small Corneal Infiltrates in Contact Lens Wearers. Arch Ophthalmol. 2000;118(2):276-277. doi:10.1001/archopht.118.2.276