SYSTEMIC LUPUS erythematosus is an autoimmune disease associated with polyclonal B-cell activation and production of autoantibodies. Systemic lupus erythematosus can affect multiple organ systems, including the eye.1
A 31-year-old woman noted blurred vision in both eyes during hospitalization for an exacerbation of systemic lupus erythematosus. Her medications included 60 mg of prednisone per day. Seventeen years prior to our seeing her she had taken an unknown dose of hydroxychloroquine sulfate for 1 year. Results of prior retinal examinations were not available, but the patient reported previously normal vision in both eyes.
Read RW, Chong LP, Rao NA. Occlusive Retinal Vasculitis Associated With Systemic Lupus Erythematosus. Arch Ophthalmol. 2000;118(4):588-589. doi:10.1001/archopht.118.4.588